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This Concept Map, created with IHMC CmapTools, has information related to: Gram Positive Rods, Nocardia Asteroides Diseases Caused Nocardosis (Usually immunocompromised; Fever, cough, PNA w/ cavitations), Gram Positive Rods Nocardia Asteroides, Gram Positive Rods Actinomyces Israelii, Corynebacterium Diphtheriae Diseases Caused -Diphtheria (Gray pseudomembrane that can cause respiratory obstruction) -Bull Neck, Bacillus Anthracis Virulence Factors -Spore Forming -Antiphagocytic Capsule -Edema Factor (Exo; increases cAMP) -Lethal Factor (Exo; Causes tissue necrosis) -Protective Factor (Exo; Allows entry of toxins into target cells), Clostridium Tetani Diseases Caused Tetanus (Trismus or Lockjaw; risus sardonicus; spastic paralysis), Mycobacteria Leprae Diseases Caused Leprosy (Granulomas in nervous tissue), Clostridium Tetani Virulence Factors -Tetanus Toxin -Classic AB Toxin (Targets GABA and Glycine), Mycobacteria Leprae Characteristics -Obligate Intracellular -Slow growing bacteria, Gram Positive Rods Spore Forming Clostridium Tetani, Corynebacterium Diphtheriae Virulence Factors AB toxin that inhibits EF2, Bacillus Anthracis Gram Positive Rods, Gram Positive Rods Corynebacterium Diphtheriae, Actinomyces Israelii Diseases Caused -Cervicofacial Infections* (Draining of sinus tracts) -Thoracic Infections -Abdominal Infections, Listeria Monocytogenes Diseases Caused -Granulomatosis Infantiseptica -Meningitis (Shortly after birth) -Flu like sx w/ or w/o gastroenterits, Listeria Monocytogenes Characteristics -Coccobacilli -Grows at 4 degrees celcius and high salt concentration -Intracellular -Actin Rockets***, Gram Positive Rods Spore Forming Clostridium Botulinum, Actinomyces Israelii Characteristics -Obligate Anaerobe -Yellow Sulfur Granules -Filamentous Rods, Gram Positive Rods Bacillus Cereus, Clostridium Botulinum Virulence Factors -Botulinum Toxin -Classic AB Toxin (Targets Ach)